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| Title | Ries Lab at |
| Description | Website of the Ries Lab at EMBL |
| Keywords | EMBL, EMBL Heidelberg, Ries Lab, Jonas Ries, Localization Microscopy, SMLM, Superresolution Microscopy, Fluorescence Microscopy, Microscopy, Microscopy Development, Software Development, Single Molecule, Fitting, iPALM, 4 Pi Microscope, SALM |
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| Location | Germany |
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Zuletzt aktualisiert: 2022-06-09 02:59:43
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| HOME Menu Research People Gallery Software Resources Publications Contact Ries Lab Superresolution Microscopy for Structural Cell Biology We develop superresolution microscopy technologies to visualize the structure and dynamics of molecular machines in cells on the nanoscale. We use these techniques to investigate the dynamic structural organization of the machinery that drives clathrin-mediated endocytosis. Research in the Ries Lab Previous and current research Like nanoscopic machines, protein assemblies carry out a multitude of cellular processes. Understanding their function and mechanics requires knowing their in situ structural organisation and dynamics, which are barely accessible to classical structural biology techniques (EM, NMR, crystallography). Superresolution microscopy, and specifically Single-Molecule Localization Microscopy (SMLM), is an ideal tool to study these assemblies in their natural cellular environment and to understand their modus operandi. In our group, we |
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